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Society of Nuclear Medicine and Molecular Imaging Annual Meeting 2017

David T. Drummond ⎜Jun 2, 2017 ⎜ Calendar

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2017 June 10 to 14 @ The Colorado Convention Center, 700 14th St, Denver, CO 80202

isoSolutions is pleased to inform you that we will attend the Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI). You can find us at Booth 931 in the Colorado Convention Center. We hope to see you there and we can arrange a time and place to meet if you wish.

We look forward to seeing you in Denver, Colorado.

Report warns of shortages to Mo-99 supply in U.S.

David T. Drummond ⎜Sep 15, 2016 ⎜ Market

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“This is a period of profound change for the Mo-99 supply network that is key to our industry.” – David Drummond, Managing Director and Founder of isoSolutions.

By Wayne Forrest, www.auntminnie.comoriginal link

September 13, 2016 — Supplies of a key radioisotope used in nuclear cardiology scans could be disrupted next month when a Canadian nuclear reactor begins shutting down. U.S. healthcare providers could be left scrambling for new sources of molybdenum-99 (Mo-99) until other suppliers are able to step in and fill the void.
That’s according to the National Academies of Sciences, Engineering, and Medicine (NAS), which in a new report predicts a greater than 50% likelihood of a “severe” global medical isotope shortage as Canadian Nuclear Laboratories (CNL) ceases routine production of Mo-99 next month at its National Research Universal (NRU) reactor in Chalk River, Ontario.

The new report also forewarned that European suppliers’ projects to convert Mo-99 production to low-enriched uranium could further exacerbate the Mo-99 shortage in 2017 and 2018. In many ways, the NAS forecast is a best-case scenario predicated on Mo-99 suppliers completing their projects on time with no startup delays.

To help alleviate the potential isotope shortfall, the NAS recommended that the U.S. government “continue to work with the Canadian government to ensure that there is an executable and well-communicated plan in place to restart Canadian supply of molybdenum-99 after October 2016.”

CNL reactor plans

CNL plans to keep the NRU reactor on “hot standby” beyond next month as the facility is considered a “supplier of last resort” until the end of March 2018, according to the report. After that date, CNL will permanently shut down the reactor, which is now 58 years old.
As of this past June, approximately 95% of the global Mo-99 supply is produced at seven research reactors located in Australia, Canada, Europe, and South Africa. The other 5% is produced at other facilities for regional use.

The shuttering of the NRU reactor reduces to six the number of irradiation-services suppliers producing Mo-99, which is the raw material for technetium-99m (Tc-99m), a widely used radiopharmaceutical for nuclear cardiology and other studies. Four of those reactors are more than 50 years old. Several of the reactors have experienced unscheduled downtime for major repairs, and the NAS report stated there is “no reason to believe that such outages will not occur in the future.”
The NRU reactor’s closure also reduces the number of global Mo-99 suppliers from five to four, with three of the suppliers — the Australian Nuclear Science and Technology Organization (ANSTO), the Institute for Radioelements (IRE) in Belgium, and Mallinckrodt — currently undertaking substantial modifications to their facilities or processes.

Waiting in the wings are NTP Radioisotopes in South Africa, which has initiated plans to expand its available supply capacities, and the Russian Federation, which wants to become a global Mo-99 supplier.

U.S. production
Currently, there are three projects underway to begin Mo-99 production in the U.S.:

• Shine Medical Technologies is working to build a medical isotope manufacturing facility in Janesville, WI.
• NorthStar Medical Radioisotopes has begun routine production of Mo-99 at the University of Missouri Research Reactor in Columbia, MO.
• Coquí RadioPharmaceuticals plans to build a facility in Florida.

“However, no domestic commercial production will be established before Canada stops producing molybdenum-99 after October 2016,” according to the report. “Potential domestic molybdenum-99 suppliers face technical, financial, regulatory, and market penetration challenges. The market challenges will likely increase after current global suppliers expand production.”
If and when global production ventures come online, the NAS estimated they would add approximately 4,400 six-day Ci per week of available supply capacity. That contribution would offset the loss of 4,680 six-day Ci per week of available supply when the NRU reactor ramps down next month.
The burden of an Mo-99 shortage may be lessened if U.S. demand for Mo-99 and technetium-99m for medical use continues to decline, as it has for the past decade. The average decrease in U.S. Mo-99 and Tc-99m utilization from 2009-2010 to 2014-2015 was approximately 25%, according to the NAS, which found it “unlikely that domestic demand will increase significantly over the next five years.”
In the international arena, however, the NAS predicted that demand for Mo-99 will escalate over the next five years due to greater utilization in emerging Asian markets.

SNMMI reaction

The president of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), Sally Schwarz, concurred with the report’s conclusions.
“Development of these new, nonhighly enriched uranium production methods is costly, even when shared with governments,” said the professor of radiology at Washington University School of Medicine in St. Louis in a prepared statement. “It will take time and incremental changes to reach a balance point of fair reimbursement for increased costs for all members of the supply chain including Mo-99 producers, generator manufacturers, nuclear pharmacies, hospitals, and patients.”

She cautioned that while the potential for short-term shortages is a concern, she is confident global Mo-99 producers, processors, and generator manufacturers will collaborate with the Association of Imaging Producers and Equipment Suppliers to manage any interim shortages.
“The innovative, safer production methods and facilities that will be coming online over the next few years will certainly help ensure a safe, reliable supply of Mo-99,” Schwarz said.

isoSolutions Presents Wide Range of Products at Annual Meeting of Society of Nuclear Medicine and Medical Imaging

David T. Drummond ⎜Jun 1, 2016 ⎜ Calendar

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The annual meeting of the Society of Nuclear Medicine and Medical Imaging (SNNMI) will be held in Vancouver, Canada from 08 June to 12 June 2013. isoSolutions Marketing & Management Inc. will be exhibiting a wide range of nuclear medicine products.

isoSolutions is presenting a package of products and services for diagnostic and therapeutic radiolabeling applications — a complete labeling solution. isoSolutions can provide a complete range of radioisotopes, including a Ga-68 Generator (iThemba), Lu-177, Y-90, Re-188 and I-131. These products are complemented by a state-of-the-art automated labeling module (Trasis All-in-One) and a complete range of labeling peptides. Finally, expert, experienced consulting services are offered for radiochemistry, licensing (preparation of CMC sections, INDs, DMFs) and grant applications.

isoSolutions also offers an extensive catalog of radiochemicals, radiopharmaceuticals, in-vivo cold kits, stable isotopes, labeled compounds, reagents, shipping containers, laboratory equipment and calibration sources from high quality, reliable suppliers. With isoSolutions, customers can obtain a one-stop shopping service as well as technical support.

David T. Drummond, Managing Director of isoSolutions, states, “We are looking forward to welcoming our customers from North America, South America, China and elsewhere to our booth #1336 at the SNNMI exhibition. We are especially proud that this international congress is being held in our hometown of Vancouver.”

Exhibits at Nuclear Medicine Congress (2016)

David T. Drummond ⎜Jun 1, 2016 ⎜ Calendar

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The Society of Nuclear Medicine and Molecular Imaging opens today in Baltimore and isoSolutions is exhibiting and promoting its products and services.

isoSolutions provides a one-stop shopping service as well as technical support worldwide for nuclear medicine applications including: Radiochemicals, Stable isotopes, Labeled compounds, Sealed sources, Synthesizers and Peptides. A package of products and services for diagnostic or therapeutic radiolabeling applications includes a Ga-68 Generator, Lu-177, Y-90, a Re-188 Generator, I-131, I-125, O-18 Water and cyclotron products. These products are complemented by an automated labeling module for development work or preprogrammed syntheses.

The offices of isoSolutions have a global reach:

Americas: Vancouver and Montreal;

local telephone contact in Argentina, Chile, Mexico, Brazil

Europe: Budapest; Brussels

Asia: Shanghai

Middle East and Africa: Beirut

The suppliers represented by isoSolutions reliably provide high-quality products: iThemba, Trasis, IRE, Polatom, Nukem, Radqual, Izotop, Isotopia and ABT.

David Drummond, Managing Director of isoSolutions, stated: “We look forward to welcoming our customers and displaying our capabilities at our exhibit at the SNMMI congress in Baltimore.”

About isoSolutions Marketing & Management Inc.

More information on the company can be found at isoSolutions.

Exhibits at Nuclear Medicine Congress (2015)

David T. Drummond ⎜Jul 7, 2015 ⎜ Calendar

Tags.

The Society of Nuclear Medicine and Molecular Imaging opens today in Baltimore and isoSolutions is exhibiting and promoting its products and services.

isoSolutions provides a one-stop shopping service as well as technical support worldwide for nuclear medicine applications including: Radiochemicals, Stable isotopes, Labeled compounds, Sealed sources, Synthesizers and Peptides. A package of products and services for diagnostic or therapeutic radiolabeling applications includes a Ga-68 Generator, Lu-177, Y-90, a Re-188 Generator, I-131, I-125, O-18 Water and cyclotron products. These products are complemented by an automated labeling module for development work or preprogrammed syntheses.

The offices of isoSolutions have a global reach:

Americas: Vancouver and Montreal; local telephone contact in Argentina, Chile, Mexico, Brazil

Europe: Budapest; Brussels

Asia: Shanghai

Middle East and Africa: Beirut

The suppliers represented by isoSolutions reliably provide high-quality products: iThemba, Trasis, IRE, Polatom, Nukem, Radqual, Izotop, Isotopia and ABT.

David Drummond, Managing Director of isoSolutions, stated: “We look forward to welcoming our customers and displaying our capabilities at our exhibit at the SNMMI congress in Baltimore.”

About isoSolutions Marketing & Management Inc.

More information on the company can be found at isoSolutions.