Kevin Yang ⎜Feb 13, 2019 ⎜ Industry
Bone fracture healing is dependent upon the rapid migration and engraftment of bone marrow (BM) progenitor and stem cells to the site of injury. Stromal cell-derived factor-1 plays a crucial role in recruiting BM cells expressing its receptor CXCR4. Recently, a CXCR4 antagonist, plerixafor, has been used to mobilize BM cells into the blood in efforts to enhance cell migration to sites of injury presumably improving healing. (more…)
Tags: Cell Tracking isoSolutions PET Radiochemicals Research Zr-89
Kevin Yang ⎜Mar 20, 2018 ⎜ Industry
99mTc-sestamibi CZT-SPECT is technically feasible and can provide similar result to 15O-water PET for detecting impaired myocardial flow reserve and abnormal fractional flow reserve in patients with coronary artery disease. This study highlights the diagnostic value of using 99mTc -sestamibi for patients with coronary artery disease.
The WATERDAY study: Denis Agostini & Vincent (more…)
Tags: PET Radiopharmaceuticals SPECT
David T. Drummond ⎜Mar 14, 2018 ⎜ Industry
During the last decade, the utilization of 68Ga for the development of imaging agents has increased considerably with the leading position in the oncology. The imaging of infection and inflammation is lagging despite strong unmet medical needs. This review presents the potential routes for the development of 68Ga-based agents for the imaging and quantification of infection and inflammation in various diseases and connection of the diagnosis to the treatment for the individualized patient management. (more…)
Tags: Ga-68 PET Radiochemicals
David T. Drummond ⎜Nov 15, 2016 ⎜ Products
Fast implementation of positron emission tomography (PET) into clinical and preclinical studies highly demands automated synthesis for the preparation of PET radiopharmaceuticals in a safe and reproducible manner. The aim of this study was to develop automated synthesis methods for these six 18F-labeled radiopharmaceuticals produced on a routine basis at the University of Pennsylvania using (more…)
Tags: FDG HPLC PET Radiopharmaceuticals Radiotracer Synthesizers
David T. Drummond ⎜Sep 24, 2016 ⎜ Products
ln produced on a routine basis at UPENN with the Trasis AllinOne synthesizer.
By Ramona Delcea, Trasis Download pdf