Kevin Yang ⎜Feb 25, 2019 ⎜ Industry
The role of concomitant peptide receptor radionuclide therapy (PRRT) and capecitabine therapy has shown benefit in gastroenteropancreatic neuroendocrine tumors. However, data reporting its role in paraganglioma (PGL) patients is lacking. The aim of this study was to evaluate the role of combined capecitabine and 177Lu-DOTATATE in malignant PGL patients. (more…)
Tags: Capecitabine Lu-177 Paraganglioma
Kevin Yang ⎜Nov 5, 2018 ⎜ Industry
Radiolabeled somatostatin analog therapy has become an established treatment method for patients with well to moderately differentiated unresectable or metastatic neuroendocrine tumors (NETs). The most frequently used somatostatin analogs in clinical practice are octreotide and octreotate. (more…)
Kevin Yang ⎜Sep 12, 2018 ⎜ Industry
This first-in-human study demonstrated that 177Lu-EB-PSMA-617 had higher accumulation in mCRPC and that low imaging dose appears to be effective in treating tumors with high 68Ga-PSMA-617 uptakes. Elevated uptakes of 177Lu-EBPSMA-617 in kidneys and red bone marrow were well tolerated at the administered low dose. Further investigations with increased dose and frequency of administration are warranted. (more…)
Kevin Yang ⎜Sep 6, 2018 ⎜ Industry
Prostate cancer is the most frequently diagnosed malignant tumor in men worldwide. Prostate-specific membrane antigen (PSMA) is a surface molecule specifically expressed by prostate tumors and has been shown to be a valid target for internal radionuclide therapy in both preclinical and clinical settings. The most common radiotherapeutic agent is the small molecule 177Lu-PSMA-617, (more…)
Patricia Acton ⎜Sep 5, 2018 ⎜ Calendar
isoSolutions will be attending the United Pharmacy Partners (UPPI, LLC) 2018 Annual Meeting to be held in San Antonio, TX September 12 to 15, 2018. (more…)
Tags: Batch Reporting System Beta detection Beta flow monitor Beta radio-detector Cassette-based synthesis Chromatography Software Clarity Elysia-raytest Ga-68 synthesis Gamma detection Gamma flow monitor Gamma radio-detector Gamma spectroscopy Gas Chromatography GC systems HPLC isoSolutions LIMS Liquid Scintillation Liquid Scintillation Pump Lu-177 MCA Multichannel analyzer North America Nuclear Medicine PET QC QC-Cubicle Quality Control Radio Detector Radio nuclide identification Radio nuclide purity radio spectroscopy radio TLC scanners radio-flow monitor radio-HPLC radio-synthesis radio-TLC Systems Radio-tracer Radiopharmaceutical Tracer Radiopharmaceuticals Radiopharmacy Residual Solvents Control Single-use cassette synthesis SPECT QC Spectroscopy Software Sterile filter integrity test Sterility Filter Test Synthesis Modules Synthesizers Tradeshows UPPI
Hans Peng ⎜Aug 2, 2018 ⎜ Industry
Since China was the highlighted country of 2018 SNMMI in Philadelphia, several CSNM board members presented a brief report of 2018 SNMMI to the audience. One interesting fact needs attention is that Lu-177 is the most discussed topic this year not only because Lu-177 is highly in demand during SNMMI, but also more and more professors and doctors in China have realized how important and effective Lu-177 is when it is used to diagnose and treat prostate cancer. (more…)
Tags: China CSNM Lu-177 Radiochemicals SNMMI
David T. Drummond ⎜Jun 29, 2018 ⎜ Industry
PHILADELPHIA (Embargoed until 6:30 p.m. EDT, Tuesday, June 26, 2018) ‚Äì In the battle against metastatic castrate-resistant prostate cancer, studies have demonstrated a high response rate to radionuclide therapy targeting prostate specific membrane antigen (PSMA) with the radionuclide lutetium-177 (177Lu). (more…)